Institutions: University of Calgary, Departments of Radiology & Clinical Neurosciences
Research interests: fMRI methods and application; Magnetization transfer imaging
Bruce Pike investigates magnetic resonance imaging (MRI) methods and applications for basic and clinical neuroscience research. As a primary focus, he detects and measures the physiological modulations that are associated in neuronal activation and inhibition (known as fMRI). Recently, he used his methods to determine, for the first time, the relationship between regional cerebral blood flow and oxygen metabolism in the cortex over a broad range of activation and inhibition conditions in both healthy subjects and epilepsy patients. He has also developed a in vivo quantitative MR technique term magnetization transfer (MT) imaging that probes the magnetic interaction between macromolecules and water.