Institutions: McGill University, School of Communication Sciences & Disorders
Research interests: Voice disorders; Vocal fold biology, injury and repair; Computational modeling
Nicole Li-Jessen’s laboratory integrates in vitro, in vivo and in silico (computational) approaches to study vocal fold biology and wound healing. The research goal is to generate a computational platform that can guide surgeons and speech pathologists in the best methods to repair voices that have been lost. Her lab uses agent-based modeling with parallel computing and 3D visualization to simulate patient-specific vocal trauma and repair response to medical and behavioral treatments in computers. In addition, a systems biology approach is used to investigate individual genetic variance in soft tissue injury and treatment response.